The antidiabetic drug semaglutide, also known as Ozempic, has a positive effect on patients with chronic kidney damage and obesity. They have less protein in their urine, less kidney inflammation and lower blood pressure. This was demonstrated in an international study led by clinical pharmacologist Hiddo L. Heerspink from the University Medical Center Groningen in […]
Tag Archives: damage
Groundbreaking MRI study links brainstem damage to long-term Covid-19 symptoms in survivors. Test: Quantitative susceptibility mapping at 7T in Covid-19: effects on the brainstem and associations with outcomes. Photo credit: Silver Place/Shutterstock.com A recent study published in Brain performed quantitative ultrahigh-field susceptibility mapping (QSM) of the brainstem in coronavirus disease 2019 (COVID-19) survivors after hospitalization. […]
Cytotoxic T-lymphocyte antigen 4 (CTLA-4) is a protein receptor on T immune cells that prevents the cells from killing other cells, such as cancer cells. Blocking CTLA-4 with a specific antibody is an effective treatment for some cancers, but it can damage the heart. Fresh research published in FASEB Journal reveals the mechanisms involved in […]
There is still much to learn about how doxorubicin, a 50-year-old chemotherapy drug, causes its most worrisome side effects. Although it has saved many lives, the treatment sometimes causes heart damage that stiffens the heart and puts a subset of patients at risk for future heart failure. To better understand and potentially control such complications, […]
Impoverished sleep is known to escalate the risk of diabetes complications, but can too much sleep be harmful? In diabetic patients, both too little and too much sleep can damage petite blood vessels, researchers say. Microvascular complications are common, long-term problems associated with diabetes that affect the petite blood vessels. These complications typically include retinopathy […]
Childhood-onset systemic lupus erythematosus (cSLE) is a chronic, severe autoimmune disease that carries the risk of early organ damage. Identifying specific predictors in children is critical to preventing such damage. At the 2024 Congress, EULAR – the European Association of Societies for Rheumatology – held a session on pediatric rheumatology, presenting modern work on factors […]