Tag Archives: mechanisms

Scientists are discovering the mechanisms by which CDK12 changes influence the development of prostate cancer

When researchers at the University of Michigan’s Rogel Cancer Center first identified a fresh subtype of aggressive prostate cancer, they knew they had to understand how this genetic change causes cancer and how to target its treatment. In two fresh articles, both published in Medicine Cell Reportsare doing both, describing the mechanisms of how changes […]

Study of the mechanisms of cell migration and growth

The National Institute of General Medical Sciences, a division of the National Institutes of Health (NIH), has awarded Yubing Sun, associate professor of mechanical and industrial engineering at the University of Massachusetts Amherst, a $1.9 million Maximizing Investigators’ Research Award to support her exploration of the fundamental principles behind the process of closing injury- or […]

Fresh study reveals mechanisms behind heart damage caused by CTLA-4 blockade

Cytotoxic T-lymphocyte antigen 4 (CTLA-4) is a protein receptor on T immune cells that prevents the cells from killing other cells, such as cancer cells. Blocking CTLA-4 with a specific antibody is an effective treatment for some cancers, but it can damage the heart. Fresh research published in FASEB Journal reveals the mechanisms involved in […]